Molecular Formula | C23H19F3N8O |
Molar Mass | 480.45 |
Density | 1.62±0.1 g/cm3(Predicted) |
Boling Point | 818.7±75.0 °C(Predicted) |
Solubility | DMSO: ≥ 30 mg/mL |
pKa | 8.76±0.30(Predicted) |
Storage Condition | -20℃ |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.081 ml | 10.407 ml | 20.814 ml |
5 mM | 0.416 ml | 2.081 ml | 4.163 ml |
10 mM | 0.208 ml | 1.041 ml | 2.081 ml |
5 mM | 0.042 ml | 0.208 ml | 0.416 ml |
biological activity | SR-3029 is a potent and selective inhibitor of casein kinase 1 δ/1 ε (CK1δ/ε), the IC50 values for CK1δ and CK1ε were 44 nM and 260 nM, respectively. |
Target | Value |
CK1δ (Cell-free assay) | 44 nM |
CK1ε (Cell-free assay) | 260 nM |